The No. 21 Missouri Tigers (16-4, 5-2 SEC) and the No. 13 Mississippi State Bulldogs (16-5, 4-4) meet Saturday at Humphrey Coliseum in Starkville. Tip-off is scheduled for 1 p.m. ET (SEC Network). Let’s analyze BetMGM Sportsbook’s college basketball odds around the Missouri vs. Mississippi State odds, and make our expert college basketball picks and predictions.
Mississippi State has won 8 of the past 9 meetings outright, while also going 8-1 against the spread (ATS) since Feb. 26, 2019. The Under has cashed in 5 in a row and 8 of the previous 9 in the series, too.
The Tigers have won 4 of the past 5 games, including an 83-82 win at No. 6 Florida Jan. 14, and Mizzou is 6-1 ATS in the past 7 outings. The Under is 6-2 in the past 8 games, too.
The Bulldogs have lost 4 out of the past 6 games, with its only victories during the span coming via OT at South Carolina and at home to Ole Miss. Their last victory in regulation was Jan. 7 at Vanderbilt as 2.5-point favorites. The Over is 4-2 in the past 6 games for Mississippi State.
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Missouri at Mississippi State odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:05 a.m. ET.
- Moneyline (ML): Missouri +200 (bet $100 to win $200) | Mississippi State -250 (bet $250 to win $100)
- Against the spread: Missouri +6.5 (-115) | Mississippi State -6.5 (-105)
- Over/Under (O/U): 149.5 (O: -110 | U: -110)
Missouri at Mississippi State picks and predictions
Prediction
Mississippi State 75, Missouri 73
Moneyline
Mississippi State (-250) will cost you 2½ times your potential return, and that’s way too much risk for not enough reward, especially in a battle between 2 ranked teams.
In addition, the Bulldogs are at home, but they haven’t been playing particularly well lately. Missouri (+200) has some marquee wins so far this season, including Q1 wins against Florida, Kansas and Ole Miss.
PASS.
Against the spread
MISSOURI +6.5 (-115) is a solid play catching more than 3 buckets. The Tigers have posted an impressive 6-1 ATS mark in the past 7 games since the ball dropped to ring in 2025.
On the flip side, Mississippi State -6.5 (-105) has failed to cover the past 6 outings, while going 4-9 ATS in 13 games since Dec. 9. In addition, the Bulldogs are 1-5 ATS in the past 6 contests at home.
Over/Under
UNDER 149.5 (-110) is the lean, but go with a half-unit play at most.
The total has cashed high in the past 3 games for Mississippi State at home, so there is obviously some concern. However, Mizzou has cashed low in 6 of the past 8 games, and the Under has cashed in 5 in a row in this series, while going 8-1 in the past 9 meetings, too.
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