Cleveland Cavaliers at Philadelphia 76ers odds, picks and predictions

The Cleveland Cavaliers (36-7) wrap up a 2-game road trip Friday against the Philadelphia 76ers (15-27). Tip-off at Wells Fargo Center is scheduled for 7 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Cavaliers vs. 76ers odds and make our expert NBA picks and predictions for the best bets.

Season series: Cavaliers lead 2-0; Cleveland won 114-106 in Philadelphia on Nov. 13, but the 76ers covered as 11-point underdogs as the Over (218.5) cashed. The home team is 2-0 against the spread (ATS) in both meetings, with the Over going 2-0 this season, and 7-1 in the past 8 in the series.

The Cavaliers lost 109-108 at the Houston Rockets Wednesday, and Cleveland is just 3-3 straight up (SU) in the past 6 games, while going 3-4 ATS in the previous 7 contests. The Over is 7-4 across the previous 11 outings.

The Sixers were pounded 144-109 at the Denver Nuggets, dropping a seventh consecutive game. Philadelphia has failed to cover the past 9 games, while the Over is 4-1 in the previous 5 contests.

Cavaliers at 76ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:22 a.m. ET.

  • Moneyline (ML): Cavaliers -500 (bet $500 to win $100) | 76ers +375 (bet $100 to win $375)
  • Against the spread: Cavaliers -10.5 (-105) | 76ers +10.5 (-115)
  • Over/Under: 228.5 (O: -110 | U: -110)

Cavaliers at 76ers key injuries

Cavaliers

  • G Caris LeVert (wrist) questionable
  • C Evan Mobley (calf) out
  • G Isaac Okoro (shoulder) out

76ers

  • C Andre Drummond (toe) out
  • C Joel Embiid (knee) out
  • G Kyle Lowry (hip) out
  • F Caleb Martin (hip) out
  • F KJ Martin (foot) out

For most recent updates: Official NBA injury report.

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Cavaliers at 76ers picks and predictions

Prediction

Cavaliers 121, 76ers 108

Moneyline

The Cavaliers (-500) would set you back 5 times your potential return, and that’s way too much risk for not nearly enough reward. Even if you were to toss Cleveland into a same-game, multi-leg or cross-sport parlay, including the Cavs makes little to no less. All of the value is sapped from your ticket including such a heavy favorite.

PASS.

Against the spread

PLAY CAVALIERS -10.5 (-105) laying the points on the road against the banged up 76ers +10.5 (-115).

Philadelphia has failed to cover the past 9 games. While Cleveland hasn’t been playing its best basketball lately, you can’t bet on the Sixers without Embiid, Lowry and several others key rotation members.

Over/Under

OVER 228.5 (-110) is the lean, but go with a half-unit play at most.

The total has gone high in 4 of the past 5 games for Philadelphia, while cashing in each of the past 3 outings at home.

For Cleveland, while the Under has hit in the past 2 outings, the Over is 5-3 across the past 8 games, and 15-6 across the previous 21 contests.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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